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Patrick Hearing Selected Research

Neoplasms (Cancer)

3/2023B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model.
1/2022Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans.
10/2019An Interaction with PARP-1 and Inhibition of Parylation Contribute to Attenuation of DNA Damage Signaling by the Adenovirus E4orf4 Protein.
1/2019Biphasic Functional Interaction between the Adenovirus E4orf4 Protein and DNA-PK.
8/2011Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors.
10/2010Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells.

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Patrick Hearing Research Topics

Disease

23Infections
03/2023 - 05/2005
7Virus Diseases (Viral Diseases)
01/2016 - 05/2003
6Neoplasms (Cancer)
03/2023 - 10/2010
3Adenoviridae Infections (Adenovirus Infections)
01/2016 - 05/2003
2Inflammation (Inflammations)
05/2024 - 01/2016
2Thrombocytosis (Thrombocythemia)
01/2022 - 12/2008
2Persistent Infection
01/2022 - 01/2020
2Leukemia
01/2020 - 04/2007
2Hemophilia A (Haemophilia)
12/2008 - 08/2004
1Colitis
05/2024
1Ulcerative Colitis
05/2024
1Kaposi Sarcoma (Kaposi's Sarcoma)
03/2023
1Retinoblastoma (Glioblastoma, Retinal)
01/2022
1COVID-19
12/2021
1RNA Virus Infections
12/2021
1Bites and Stings (Sting)
12/2021
1Zika Virus Infection
01/2020
1Plague (Bubonic Plague)
09/2016
1Breast Neoplasms (Breast Cancer)
08/2011
1Stroke (Strokes)
06/2011
1Coinfection
11/2002

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2005
8InterferonsIBA
03/2023 - 05/2007
5Antiviral Agents (Antivirals)IBA
12/2021 - 01/2016
5Viral DNAIBA
10/2019 - 05/2005
4A-Form DNA (A-DNA)IBA
12/2021 - 05/2011
3DNA (Deoxyribonucleic Acid)IBA
10/2019 - 11/2002
2Viral Core ProteinsIBA
06/2017 - 05/2011
2Viral ProteinsIBA
01/2016 - 01/2011
2adenovirus L4-22K proteinIBA
07/2013 - 10/2012
2Folic Acid (Vitamin M)FDA LinkGeneric
08/2011 - 10/2010
2Factor VIII (Coagulation Factor VIII)IBA
12/2008 - 08/2004
1Tn antigenIBA
05/2024
1Interleukin-22 (IL-22)IBA
05/2024
1MucinsIBA
05/2024
1Polysaccharides (Glycans)IBA
05/2024
1Dextran SulfateIBA
05/2024
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
03/2023
1Histone Deacetylase InhibitorsIBA
01/2022
1NucleotidesIBA
01/2022
1Cyclin-Dependent Kinase 4IBA
01/2022
1CytokinesIBA
01/2022
1Angiotensin-Converting Enzyme 2IBA
12/2021
1Interferon LambdaIBA
12/2021
1Glycoproteins (Glycoprotein)IBA
01/2020
1Poly(ADP-ribose) Polymerase InhibitorsIBA
10/2019
1HeterochromatinIBA
01/2019
1DNA-Activated Protein KinaseIBA
01/2019
1Type III Secretion SystemsIBA
09/2016
1InflammasomesIBA
09/2016
1Transcription Factors (Transcription Factor)IBA
01/2016
1ChromatinIBA
01/2016
1Trans-Activators (Trans-Acting Factor)IBA
01/2016
1HMGB1 Protein (HMG1)IBA
01/2016
1Tyrosine (L-Tyrosine)FDA Link
08/2011
1Protein Tyrosine PhosphatasesIBA
08/2011
1Adenosine Triphosphatases (ATPase)IBA
06/2011
1Capsid Proteins (Capsid Protein)IBA
01/2011
1Platelet Factor 4IBA
12/2008
1Nuclear Proteins (Protein, Nuclear)IBA
04/2007
1Arginine (L-Arginine)FDA Link
02/2005
1AcetyltransferasesIBA
05/2003
1Adenovirus Early ProteinsIBA
05/2003